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Saturday, July 23, 2011

Frank Whittle The jet engine (1930)

Frank Whittle.

Sir Frank Whittle's jet engine transformed travel. The jet engine has allowed millions of people now to do something that was barely thinkable just 70 years ago - crossing the Atlantic at speed. The Wright’s may have invented the first real aeroplane, but the credit for the invention of the jet engine goes to Sir Frank Whittle.
In the 1920’s, a young RAF man, Frank Whittle, had presented to the Air Ministry a design for a jet engine. They were unimpressed and rejected his idea. Regardless of this set-back, Whittle still patented his "turbojet engine" in 1930. His design appeared to solve the problem that had baffled inventors for some years - how do you create a chamber strong enough to house an engine that would create a lot of heat and vast directed thrust ? Many combustion chambers had simply been too weak to cope and had exploded under the strain.
Whittle’s engine had ten combustion chambers which produced impressive thrust : rather than having just one large chamber which would produce a volatile and potentially uncontrollable reaction, his engine effectively divided up the combustion created into the ten chambers but still did not decrease the power of the engines.
Increasing fears about problems in Europe, lead to the government having second thoughts about Whittle’s jet engine. In 1936, he went to Cambridge University, but he left and set up a company called Power Jets Ltd.
In 1937, using newly available alloys that were strong and light, he produced the first viable jet engine to be successfully tested in a laboratory. Now it had to be put onto a plane and the respective safety measures taken - as with all new planes.
Sir Frank Whittle in front of one of his jet engines
In 1941, a new jet fighter-prototype flew. Its successor, the Gloster Meteor, entered service with the RAF in 1944. However, the Gloster Meteor was not the first jet fighter. This claim goes to the Heinkel He 178 which first flew on August 24th 1939 - just days before World War Two started.
When the war finished, it seemed a logical move to apply this new invention to passenger planes. Journeys became quicker and the more powerful jet engine allowed passenger planes to get bigger so that more people could be carried on them.
The first proper jet engined passenger airliner is considered to be the De Haviland Comet. This came into operation in a blaze of publicity. Within two years, it was withdrawn from service after a series of tragic accidents which killed many. This, however, was not due to its jet engines but to a fault in its fuselage which lead to the pane breaking up in flight.
Boeing then took over the lead in jet-powered airliners. The Boeing 707 entered service in 1958. It was safe and allowed people to travel distances at speeds that would had been impossible just 10 years earlier. Whittle’s invention has transformed the world.



Friday, July 22, 2011

Alexander Fleming Discovered penicillin and paved the way for antibiotics (1928)


Penicillin is one of the earliest discovered and widely used antibiotic agents, derived from the Penicillium mold. Antibiotics are natural substances that are released by bacteria and fungi into the their environment, as a means of inhibiting other organisms - it is chemical warfare on a microscopic scale.

Sir Alexander Fleming

  • Alexander Fleming
  • born August. 6, 1881 , Darvel, Scotland
  • died March 11, 1955 , London, England
In 1928, Sir Alexander Fleming observed that colonies of the bacterium Staphylococcus aureus could be destroyed by the mold Penicillium notatum, proving that there was an antibacterial agent there in principle. This principle later lead to medicines that could kill certain types of disease-causing bacteria inside the body.
At the time, however, the importance of Alexander Fleming's discovery was not known. Use of penicillin did not begin until the 1940s when Howard Florey and Ernst Chain isolated the active ingredient and developed a powdery form of the medicine.

History of Penicillin

Originally noticed by a French medical student, Ernest Duchesne, in 1896. Penicillin was re-discovered by bacteriologist Alexander Fleming working at St. Mary's Hospital in London in 1928. He observed that a plate culture of Staphylococcus had been contaminated by a blue-green mold and that colonies of bacteria adjacent to the mold were being dissolved. Curious, Alexander Fleming grew the mold in a pure culture and found that it produced a substance that killed a number of disease-causing bacteria. Naming the substance penicillin, Dr. Fleming in 1929 published the results of his investigations, noting that his discovery might have therapeutic value if it could be produced in quantity.

Dorothy Crowfoot Hodgkin

Hodgkin used x-rays to find the structural layouts of atoms and the overall molecular shape of over 100 molecules including penicillin. Dorothy's discovery of the molecular layout of penicillin helped lead scientists to develop other antibiotics.

Dr. Howard Florey

It was not until 1939 that Dr. Howard Florey, a future Nobel Laureate, and three colleagues at Oxford University began intensive research and were able to demonstrate penicillin's ability to kill infectious bacteria. As the war with Germany continued to drain industrial and government resources, the British scientists could not produce the quantities of penicillin needed for clinical trials on humans and turned to the United States for help. They were quickly referred to the Peoria Lab where scientists were already working on fermentation methods to increase the growth rate of fungal cultures. One July 9, 1941, Howard Florey and Norman Heatley, Oxford University Scientists came to the U.S. with a small but valuable package containing a small amount of penicillin to begin work.
Pumping air into deep vats containing corn steep liquor (a non-alcoholic by-product of the wet milling process) and the addition of other key ingredients was shown to produce faster growth and larger amounts of penicillin than the previous surface-growth method. Ironically, after a worldwide search, it was a strain of penicillin from a moldy cantaloupe in a Peoria market that was found and improved to produce the largest amount of penicillin when grown in the deep vat, submerged conditions.

Andrew J. Moyer..

By November 26, 1941, Andrew J. Moyer, the lab's expert on the nutrition of molds, had succeeded, with the assistance of Dr. Heatley, in increasing the yields of penicillin 10 times. In 1943, the required clinical trials were performed and penicillin was shown to be the most effective antibacterial agent to date. Penicillin production was quickly scaled up and available in quantity to treat Allied soldiers wounded on D-Day. As production was increased, the price dropped from nearly priceless in 1940, to $20 per dose in July 1943, to $0.55 per dose by 1946.
As a result of their work, two members of the British group were awarded the Nobel Prize. Dr. Andrew J. Moyer from the Peoria Lab was inducted into the Inventors Hall of Fame and both the British and Peoria Laboratories were designated as International Historic Chemical Landmarks.

Andrew J Moyer Patent

On May 25, 1948, Andrew J Moyer was granted a patent for a method of the mass production of penicillin.

Resistance to Penicillin

Four years after drug companies began mass-producing penicillin in 1943, microbes began appearing that could resist it.
The first bug to battle penicillin was Staphylococcus aureus. This bacterium is often a harmless passenger in the human body, but it can cause illness, such as pneumonia or toxic shock syndrome, when it overgrows or produces a toxin.
Sir Howard Florey
Sir Alexander Fleming.

Thursday, July 21, 2011

John Logie Baird Invented the television - its first public demonstration was at Selfridges in London (1925)


John Logie  Baird
 


John Logie Baird was born on August 13th, 1888, in Helensburgh, Dunbarton, Scotland and died on June 14th, 1946, in Bexhill-on-Sea, Sussex, England. John Baird received a diploma course in electrical engineering at the Glasgow and West of Scotland Technical College (now called Strathclyde University), and studied towards his Bachelor of Science Degree in electrical engineering from the University of Glasgow, interrupted by the outbreak of W.W.I.

John Baird - Mechanical Television System

Baird is best remembered for inventing a mechanical television system. During the 1920's, John Baird and American Clarence W. Hansell patented the idea of using arrays of transparent rods to transmit images for television and facsimiles respectively.
Baird's 30 line images were the first demonstrations of television by reflected light rather than back-lit silhouettes. John Baird based his technology on Paul Nipkow's scanning disk idea and later developments in electronics.

John Baird Milestones

The television pioneer created the first televised pictures of objects in motion (1924), the first televised human face (1925) and a year later he televised the first moving object image at the Royal Institution in London. His 1928 trans-atlantic transmission of the image of a human face was a broadcasting milestone. Color television (1928), stereoscopic television and television by infra-red light were all demonstrated by Baird before 1930. He successfully lobbied for broadcast time with the British Broadcasting Company, the BBC started broadcasting television on the Baird 30-line system in 1929. The first simultaneous sound and vision telecast was broadcast in 1930. In July 1930, the first British Television Play was transmitted, "The Man with the Flower in his Mouth."
In 1936, the British Broadcasting Corporation adopted television service using the electronic television technology of Marconi-EMI (the world's first regular high resolution service - 405 lines per picture), it was that technology that won out over Baird's system.

Wednesday, July 20, 2011

Clarence Birdseye Started the idea of frozen food (1924)

CLARENCE BIRDSEYE (1886-1956)
Retail Frozen Foods
ClarenceClarence Birdseye found a way to flash-freeze foods and deliver them to the public---one of the most important steps forward ever taken in the food industry.
Born in Brooklyn in 1886, Birdseye was a biology major at Amherst College when quit school to work as a naturalist for the US government. He was posted to the Arctic, where he observed first-hand the ways of the native Americans who lived there. Birdseye saw that the combination of ice, wind and temperature almost instantly froze just-caught fish straight through. More importantly, he found that when the fish were cooked and eaten, they were scarcely different in taste and texture than they would have been if fresh.
Birdseye the biologist saw that the fish were frozen too quickly for ice crystals to form and ruin their cellular structure. Birdseye the businessman saw that the public back home would gladly pay for such frozen foods, if he could deliver them. He returned to New York, and in 1924 founded Birdseye Seafoods, Inc.

PressIn the early 1900s, many people were experimenting with mechanical and chemical methods to preserve food. After years of work on his own process, Birdseye invented a system that packed dressed fish, meat or vegetables into waxed-cardboard cartons, which were flash-frozen under high pressure (patent #1,773,079, 1930).
Birdseye now turned to marketing. He tested refrigerated grocery display cases in 1930, and entered a joint venture to manufacture them in 1934. In 1944, Birdseye's company began leasing refrigerated boxcars to transport the frozen foods by rail nationwide. This made national distribution a reality, and Birdseye a legend.
Today, we especially appreciate that Birdseye's process, still basically in use, preserves foods' nutrients as well as their flavor. In fact, we can say that Clarence Birdseye has indirectly improved both the health and convenience of virtually everyone in the industrialized world.



Tuesday, July 19, 2011

Karol Capek; Discovered the Robot



Definition of a 'Robot'
According to the Robot Institute of America (1979) a robot is:
"A reprogrammable, multifunctional manipulator designed to move material, parts, tools, or specialized devices through various programmed motions for the performance of a variety of tasks".

A more inspiring definition can be found in Webster. According to Webster a robot is:
"An automatic device that performs functions normally ascribed to humans or a machine in the form of a human."
First use of the word 'robot'
Karel CapekThe acclaimed Czech playwright Karel Capek (1890-1938) made the first use of the word ‘robot’, from the Czech word for forced labor or serf. Capek was reportedly several times a candidate for the Nobel prize for his works and very influential and prolific as a writer and playwright.

The use of the word Robot was introduced into his play R.U.R. (Rossum's Universal Robots) which opened in Prague in January 1921.

In R.U.R., Capek poses a paradise, where the machines initially bring so many benefits but in the end bring an equal amount of blight in the form of unemployment and social unrest.

The play was an enormous success and productions soon opened throughout Europe and the U.S. R.U.R's theme, in part, was the dehumanization of man in a technological civilization.

You may find it surprising that the robots were not mechanical in nature but were created through chemical means. In fact, in an essay written in 1935, Capek strongly fought that this idea was at all possible and, writing in the third person, said:

"It is with horror, frankly, that he rejects all responsibility for the idea that metal contraptions could ever replace human beings, and that by means of wires they could awaken something like life, love, or rebellion. He would deem this dark prospect to be either an overestimation of machines, or a grave offence against life."
[The Author of Robots Defends Himself - Karl Capek, Lidove noviny, June 9, 1935, translation: Bean Comrada]

There is some evidence that the word robot was actually coined by Karl's brother Josef, a writer in his own right. In a short letter, Capek writes that he asked Josef what he should call the artificial workers in his new play.

Karel suggests Labori, which he thinks too 'bookish' and his brother mutters "then call them Robots" and turns back to his work, and so from a curt response we have the word robot.
First use of the word 'robotics'
Isaac AsimovThe word 'robotics' was first used in Runaround, a short story published in 1942, by Isaac Asimov (born Jan. 2, 1920, died Apr. 6, 1992). I, Robot, a collection of several of these stories, was published in 1950.

One of the first robots Asimov wrote about was a robotherapist. A modern counterpart to Asimov's fictional character is Eliza. Eliza was born in 1966 by a Massachusetts Institute of Technology Professor Joseph Weizenbaum who wrote Eliza -- a computer program for the study of natural language communication between man and machine.

She was initially programmed with 240 lines of code to simulate a psychotherapist by answering questions with questions.
Three Laws of Robotics
Asimov also proposed his three "Laws of Robotics", and he later added a 'zeroth law'.

Law Zero: A robot may not injure humanity, or, through inaction, allow humanity to come to harm.
Law One: A robot may not injure a human being, or, through inaction, allow a human being to come to harm, unless this would violate a higher order law.
Law Two: A robot must obey orders given it by human beings, except where such orders would conflict with a higher order law.
Law Three: A robot must protect its own existence as long as such protection does not conflict with a higher order law.
The First Robot: 'Unimate'
Unimate Puma500 ManipulatorAfter the technology explosion during World War II, in 1956, a historic meeting occurs between George C. Devol, a successful inventor and entrepreneur, and engineer Joseph F. Engelberger, over cocktails the two discuss the writings of Isaac Asimov.

Together they made a serious and commercially successful effort to develop a real, working robot. They persuaded Norman Schafler of Condec Corporation in Danbury that they had the basis of a commercial success.

Engelberger started a manufacturing company 'Unimation' which stood for universal automation and so the first commercial company to make robots was formed. Devol wrote the necessary patents. Their first robot nicknamed the 'Unimate'. As a result, Engelberger has been called the 'father of robotics.'

The first Unimate was installed at a General Motors plant to work with heated die-casting machines. In fact most Unimates were sold to extract die castings from die casting machines and to perform spot welding on auto bodies, both tasks being particularly hateful jobs for people.

Both applications were commercially successful, i.e., the robots worked reliably and saved money by replacing people. An industry was spawned and a variety of other tasks were also performed by robots, such as loading and unloading machine tools.

Ultimately Westinghouse acquired Unimation and the entrepreneurs' dream of wealth was achieved. Unimation is still in production today, with robots for sale.

The robot idea was hyped to the skies and became high fashion in the Boardroom. Presidents of large corporations bought them, for about $100,000 each, just to put into laboratories to "see what they could do;" in fact these sales constituted a large part of the robot market. Some companies even reduced their ROI (Return On Investment criteria for investment) for robots to encourage their use.
Modern Industrial Robots
The image of the "electronic brain" as the principal part of the robot was pervasive. Computer scientists were put in charge of robot departments of robot customers and of factories of robot makers. Many of these people knew little about machinery or manufacturing but assumed that they did.

(There is a common delusion of electrical engineers that mechanical phenomena are simple because they are visible. Variable friction, the effects of burrs, minimum and redundant constraints, nonlinearities, variations in workpieces, accommodation to hostile environments and hostile people, etc. are like the "Purloined Letter" in Poe's story, right in front of the eye, yet unseen.) They also had little training in the industrial engineer's realm of material handling, manufacturing processes, manufacturing economics and human behavior in factories.

As a result, many of the experimental tasks in those laboratories were made to fit their robot's capabilities but had little to do with the real tasks of the factory.

Modern industrial arms have increased in capability and performance through controller and language development, improved mechanisms, sensing, and drive systems. In the early to mid 80's the robot industry grew very fast primarily due to large investments by the automotive industry.

The quick leap into the factory of the future turned into a plunge when the integration and economic viability of these efforts proved disastrous. The robot industry has only recently recovered to mid-80's revenue levels.

In the meantime there has been an enormous shakeout in the robot industry. In the US, for example, only one US company, Adept, remains in the production industrial robot arm business. Most of the rest went under, consolidated, or were sold to European and Japanese companies.

In the research community the first automata were probably Grey Walter's machina (1940's) and the John's Hopkins beast. Teleoperated or remote controlled devices had been built even earlier with at least the first radio controlled vehicles built by Nikola Tesla in the 1890's.

Tesla is better known as the inventor of the induction motor, AC power transmission, and numerous other electrical devices. Tesla had also envisioned smart mechanisms that were as capable as humans.

An excellent biography of Tesla is Margaret Cheney's Tesla, Man Out of Time, Published by Prentice-Hall, c1981.

SRI's Shakey navigated highly structured indoor environments in the late 60's and Moravec's Stanford Cart was the first to attempt natural outdoor scenes in the late 70's.

From that time there has been a proliferation of work in autonomous driving machines that cruise at highway speeds and navigate outdoor terrains in commercial applications.

Fully functioning androids (robots that look like human beings) are many years away due to the many problems that must be solved. However, real, working, sophisticated robots are in use today and they are revolutionizing the workplace.

These robots do not resemble the romantic android concept of robots. They are industrial manipulators and are really computer controlled "arms and hands". Industrial robots are so different to the popular image that it would be easy for the average person not to recognize one.
Benefits
Robots offer specific benefits to workers, industries and countries. If introduced correctly, industrial robots can improve the quality of life by freeing workers from dirty, boring, dangerous and heavy labor. it is true that robots can cause unemployment by replacing human workers but robots also create jobs: robot technicians, salesmen, engineers, programmers and supervisors.
The benefits of robots to industry include improved management control and productivity and consistently high quality products. Industrial robots can work tirelessly night and day on an assembly line without an loss in performance.

Consequently, they can greatly reduce the costs of manufactured goods. As a result of these industrial benefits, countries that effectively use robots in their industries will have an economic advantage on world market.

Monday, July 18, 2011

Frederick Banting / Charles Best Isolated insulin (1921)


Frederick Banting.

Charles Best.
In 1920, Dr. Frederick Banting wanted to make a pancreatic extract, which he hoped would have anti-diabetic qualities. In 1921, at the University of Toronto, Canada, along with medical student Charles Best, they managed to make the pancreatic extract.

Their method involved tying a string around the pancrease duct. When examined several weeks later, the pancreatic digestive cells had died and been absorbed by the immune system. The process left behind thousands of islets. They isolated the extracts from the islets and produced isletin. What they called isletin became known as insulin.

Banting and Best managed to test this extract on dogs that had diabetes. They discovered insulin. In fact, they managed to keep a dog, that had had its pancreas taken out, alive throughout the whole summer by administering it the extract (which was, in fact, insulin). The extract regulated the dogs blood sugar levels.
j.b. collipAt this point, Professor J. MacLeod, who had placed the laboratory at their disposal, said he wanted to see a re-run of the whole trial. After doing so he decided to get his whole research team to work on the production and purification of insulin.

J.B. Collip joined the scientific team, which now consisted of Banting, Best, Collip and MecLeod. They managed to produce enough insulin, in a pure enough form, to be able to test it on patients.

In 1922 the insulin was tested on Leonard Thompson, a 14-year-old diabetes patient who lay dying at the Toronto General Hospital. He was given an insulin injection. At first he suffered a severe allergic reaction and further injections were cancelled. The scientists worked hard on improving the extract and then a second dose of injections were administered on Thompson. The results were spectacular.

The scientists went to the other wards with diabetic children, most of them comatose and dying from diabetic keto-acidosis. 
j. macleodThey went from bed-to-bed and injected them with the new purified extract - insulin. This is known as one of medicines most dramatic moments. Before injecting the last comatose children, the first started to awaken from their comas. A joyous moment for family members and hospital staff!!

Collip did not get on too well with Banting and Best apparently - and he soon left the project. Best continued trying to improve the extract and managed eventually to produce enough for the hospital's demand. Their work was privately published. The Eli Lilly Company soon got to hear about it and offered to assist. It was not long before the Eli Lilly Company managed to produce large quantities of refined pure insulin.

In 1923 Banting and Macleod were awarded the Nobel Prize in Physiology or Medicine. Banting shared his prize with Best and Macleod shared his with Collip. The patent for insulin was sold to the University of Toronto for one dollar.

Sunday, July 17, 2011

The Invention of the zip

In 1893 Whitcomb Judson of Chicago (who also invented the 'Pneumatic Street Railway') marketed a 'Clasp Locker' a complicated hook-and-eye shoe fastener. The clasp locker was an assemblage of hooks and eyes that Judson thought would save people time and sore backs fastening their shoes with one hand. Together with businessman Colonel Lewis Walker, Whitcomb launched the Universal Fastener Company to manufacture the new device.
Swedish immigrant and electrical engineer, Gideon Sundback was hired
 

to work for the Universal Fastener Company. Good design skills and a marriage to the plant-manager's daughter Elvira Aronson led Sundback to the position of head designer at Universal. He was responsible for improving the far from perfect 'Judson C-curity Fastener.' Unfortunately, Sundback's wife died in 1911. The grieving husband busied himself at the design table, by December of 1913, he came up with the modern zipper.
Sundback increased the number of fastening elements from four per inch to ten or eleven, had two facing-rows of teeth that pulled into a single piece by the slider, and increased the opening for the teeth guided by the slider. The patent for the 'Separable Fastener' was issued in 1917. Sundback also created the manufacturing machine for the new zipper. The 'S-L' or scrapless machine took a special Y-shaped wire and cut scoops from it, then punched the scoop dimple and nib, and clamped each scoop on a cloth tape to produce a continuous zipper chain. Within the first year of operation, Sundback's zipper-making machinery was producing a few hundred feet of fastener per day.
The popular 'zipper' name came from B. F. Goodrich Company president Bertram G. Wrok, when they decided to use Gideon's fastener on his "Mystic Boot", which were rubber boots or galoshes, and called it the Zipper Boot.
Boots and tobacco pouches with a zippered closure were the two chief uses of the zipper during its early years. It took twenty more years to convince the fashion industry to seriously promote the novel closure on garments.
In the 1930’s, a sales campaign began for children's clothing featuring zippers. The campaign praised zippers for promoting self-reliance in young children by making it possible for them to dress in self-help clothing.
Not until 1934 when Lord Louis Mountbaten persuaded the Prince of Wales and George, Duke of York to give up their buttons for zipper flies. Tailors who disdained zipper flies as vulgar created a fold of cloth to conceal the zipper.
YKK. In 1934
Yoshida Kogyo Kabushililaisha was founded. Sixty years later they changed their name to YKK Co. The privately owned firm, headquartered in Japan, now is made up of 80 companies at 206 facilities in 52 countries.
The zipper beat the button in the 1937 in the "Battle of the Fly," when French fashion designers raved over zippers in men's trousers. Esquire magazine declared the zipper the "Newest Tailoring Idea for Men" and among the zippered fly's many virtues was that it would exclude "The Possibility of Unintentional and Embarrassing Disarray." Obviously, the new zippered trouser owners had not yet discovered the experience of forgetting to zip-up.
The next big boost for the zipper came when zippers could open on both ends, as on jackets. Today the zipper is everywhere, in clothing, luggage and leather goods and countless other objects. Thousands of  zipper miles produced daily meet the needs of consumers, thanks to the early efforts of the many famous zipper inventors.