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Thursday, January 13, 2011

Nobel Prize in Medicine; 1976

Baruch S. Blumberg
D. Carleton Gajdusek

Baruch S. Blumberg

D. Carleton Gajdusek

The Nobel Prize in Physiology or Medicine 1976 was awarded jointly to Baruch S. Blumberg and D. Carleton Gajdusek "for their discoveries concerning new mechanisms for the origin and dissemination of infectious diseases"

Alfred Nobel; Founder of the Nobel Prize.(From the Nobel Foundation Ardhives)

Alfred Nobel - His Life and Work

Alfred Nobel was born in Stockholm on October 21, 1833. His father Immanuel Nobel was an engineer and inventor who built bridges and buildings in Stockholm. In connection with his construction work Immanuel Nobel also experimented with different techniques for blasting rocks.
Alfred Nobel
Alfred Nobel
Alfred's mother, born Andriette Ahlsell, came from a wealthy family. Due to misfortunes in his construction work caused by the loss of some barges of building material, Immanuel Nobel was forced into bankruptcy the same year Alfred Nobel was born. In 1837 Immanuel Nobel left Stockholm and his family to start a new career in Finland and in Russia. To support the family, Andriette Nobel started a grocery store which provided a modest income. Meanwhile Immanuel Nobel was successful in his new enterprise in St. Petersburg, Russia. He started a mechanical workshop which provided equipment for the Russian army and he also convinced the Tsar and his generals that naval mines could be used to block enemy naval ships from threatening the city.
 Immanuel Nobel  Andriette Nobel
Immanuel Nobel Andriette Nobel(Alfre Nobel's parents)
The naval mines designed by Immanuel Nobel were simple devices consisting of submerged wooden casks filled with gunpowder. Anchored below the surface of the Gulf of Finland, they effectively deterred the British Royal Navy from moving into firing range of St. Petersburg during the Crimean war (1853-1856). Immanuel Nobel was also a pioneer in arms manufacture and in designing steam engines
.
 naval mines
Painting by Immanuel Nobel demonstrating his sea or naval mines to the Tsar of Russia.
Successful in his industrial and business ventures, Immanuel Nobel was able, in 1842, to bring his family to St. Petersburg. There, his sons were given a first class education by private teachers. The training included natural sciences, languages and literature. By the age of 17 Alfred Nobel was fluent in Swedish, Russian, French, English and German. His primary interests were in English literature and poetry as well as in chemistry and physics. Alfred's father, who wanted his sons to join his enterprise as engineers, disliked Alfred's interest in poetry and found his son rather introverted. In order to widen Alfred's horizons his father sent him abroad for further training in chemical engineering. During a two year period Alfred Nobel visited Sweden, Germany, France and the United States. In Paris, the city he came to like best, he worked in the private laboratory of Professor T. J. Pelouze, a famous chemist. There he met the young Italian chemist Ascanio Sobrero who, three years earlier, had invented nitroglycerine, a highly explosive liquid. Nitroglycerine was produced by mixing glycerine with sulfuric and nitric acid. It was considered too dangerous to be of any practical use. Although its explosive power greatly exceeded that of gunpowder, the liquid would explode in a very unpredictable manner if subjected to heat and pressure. Alfred Nobel became very interested in nitroglycerine and how it could be put to practical use in construction work. He also realized that the safety problems had to be solved and a method had to be developed for the controlled detonation of nitroglycerine. In the United States he visited John Ericsson, the Swedish-American engineer who had developed the screw propeller for ships. In 1852 Alfred Nobel was asked to come back and work in the family enterprise which was booming because of its deliveries to the Russian army. Together with his father he performed experiments to develop nitroglycerine as a commercially and technically useful explosive. As the war ended and conditions changed, Immanuel Nobel was again forced into bankruptcy. Immanuel and two of his sons, Alfred and Emil, left St. Petersburg together and returned to Stockholm. His other two sons, Robert and Ludvig, remained in St. Petersburg. With some difficulties they managed to salvage the family enterprise and then went on to develop the oil industry in the southern part of the Russian empire. They were very successful and became some of the wealthiest persons of their time.
Explosion in the laboratory in Stockholm.
After his return to Sweden in 1863, Alfred Nobel concentrated on developing nitroglycerine as an explosive. Several explosions, including one (1864) in which his brother Emil and several other persons were killed, convinced the authorities that nitroglycerine production was exceedingly dangerous. They forbade further experimentation with nitroglycerine within the Stockholm city limits and Alfred Nobel had to move his experimentation to a barge anchored on Lake Mälaren. Alfred was not discouraged and in 1864 he was able to start mass production of nitroglycerine. To make the handling of nitroglycerine safer Alfred Nobel experimented with different additives. He soon found that mixing nitroglycerine with kieselguhr would turn the liquid into a paste which could be shaped into rods of a size and form suitable for insertion into drilling holes. In 1867 he patented this material under the name of dynamite. To be able to detonate the dynamite rods he also invented a detonator (blasting cap) which could be ignited by lighting a fuse. These inventions were made at the same time as the diamond drilling crown and the pneumatic drill came into general use. Together these inventions drastically reduced the cost of blasting rock, drilling tunnels, building canals and many other forms of construction work.
 laboratory
Alfred Nobel's laboratory in Bofors, Sweden.

The market for dynamite and detonating caps grew very rapidly and Alfred Nobel also proved himself to be a very skillful entrepreneur and businessman. By 1865 his factory in Krümmel near Hamburg, Germany, was exporting nitroglycerine explosives to other countries in Europe, America and Australia. Over the years he founded factories and laboratories in some 90 different places in more than 20 countries. Although he lived in Paris much of his life he was constantly traveling. Victor Hugo at one time described him as "Europe's richest vagabond". When he was not traveling or engaging in business activities Nobel himself worked intensively in his various laboratories, first in Stockholm and later in Hamburg (Germany), Ardeer (Scotland), Paris and Sevran (France), Karlskoga (Sweden) and San Remo (Italy). He focused on the development of explosives technology as well as other chemical inventions, including such materials as synthetic rubber and leather, artificial silk, etc. By the time of his death in 1896 he had 355 patents.
Intensive work and travel did not leave much time for a private life. At the age of 43 he was feeling like an old man. At this time he advertised in a newspaper "Wealthy, highly-educated elderly gentleman seeks lady of mature age, versed in languages, as secretary and supervisor of household." The most qualified applicant turned out to be an Austrian woman, Countess Bertha Kinsky. After working a very short time for Nobel she decided to return to Austria to marry Count Arthur von Suttner. In spite of this Alfred Nobel and Bertha von Suttner remained friends and kept writing letters to each other for decades. Over the years Bertha von Suttner became increasingly critical of the arms race. She wrote a famous book, Lay Down Your Arms and became a prominent figure in the peace movement. No doubt this influenced Alfred Nobel when he wrote his final will which was to include a Prize for persons or organizations who promoted peace. Several years after the death of Alfred Nobel, the Norwegian Storting (Parliament) decided to award the 1905 Nobel Peace Prize to Bertha von Suttner.
Bertha von Suttner
Alfred Nobel's greatness lay in his ability to combine the penetrating mind of the scientist and inventor with the forward-looking dynamism of the industrialist. Nobel was very interested in social and peace-related issues and held what were considered radical views in his era. He had a great interest in literature and wrote his own poetry and dramatic works. The Nobel Prizes became an extension and a fulfillment of his lifetime interests.
Many of the companies founded by Nobel have developed into industrial enterprises that still play a prominent role in the world economy, for example Imperial Chemical Industries (ICI), Great Britain; Société Centrale de Dynamite, France; and Dyno Industries in Norway. Toward the end of his life, he acquired the company AB Bofors in Karlskoga, where Björkborn Manor became his Swedish home. Alfred Nobel died in San Remo, Italy, on December 10, 1896. When his will was opened it came as a surprise that his fortune was to be used for Prizes in Physics, Chemistry, Physiology or Medicine, Literature and Peace. The executors of his will were two young engineers, Ragnar Sohlman and Rudolf Lilljequist. They set about forming the Nobel Foundation as an organization to take care of the financial assets left by Nobel for this purpose and to coordinate the work of the Prize-Awarding Institutions. This was not without its difficulties since the will was contested by relatives and questioned by authorities in various countries.
 Ragnar Sohlman
Ragnar Sohlman

Wednesday, January 12, 2011

Swami Vivekananda's Birthday

DEAR ALL,
SWAMI VIVEKANANDA JAYANTHI,  JANUARY 12 2011
Swami Vivekananda was born in Calcutta (Now Kolkata) Monday in a traditional family, on 12 January. His father Vishwanath Dutta was an attorney of Calcutta High Court. He was considered generous, and
had a liberal and progressive outlook in social and religious matters. His mother Bhuvaneshwari Devi was pious and had practiced austerities and a devotee of Lord Shiva. Swami Vivekananda’s thinking and personality were influenced by his parents—the father by his rational mind and the mother by her religious temperament. From his mother he learnt the power of self-control. 
 
Swami Vivekananda taught the principles of the universe, and his teachings are popular even today. His ageless words will touch the life of all. No matter whether old or young; the spiritual messages quotations and sayings of great Swami Vivekananda will bring wisdom and enlighten our life.
He was a man of great brilliance and had a tremendous presence. I am sharing some of the quotes.


Religion is not in doctrines, in dogmas, nor in intellectual argumentation,
It is being and becoming, it is realization.

The greatest religion is to be true to your own nature. Have faith in yourselves."

First of all, our young men must be strong. Religion will come afterwards. Be strong, my young friends; that is my advice to you.

The secret of religion lies not in theories but in practice. To be good and do good - that is the whole of religion.

The very fact of disputations and fighting among sects shows that they do not know anything about religion. Religion to them is a mere mass of frothy words, to be written in books.
Religion is not going to church, or putting marks on the forehead, or dressing in a peculiar fashion. You may paint yourselves in all the colours of the rainbow, but if the heart has not been opened, if you have not realized God, it is all vain.
The basic aim of religion is to bring peace to man. It is not a wise thing for one to suffer in this life so that one can be happy in the next. One must be happy here and now. Any religion that can bring that
about is the true religion for humanity.
TRUTH:

Truth, purity, and unselfishness - whenever these are present, there is no power below or above the sun to crush the possessor thereof. Equipped with these, one individual is able to face the whole universe in opposition.

Everything can be sacrificed for truth, but truth cannot be sacrificed for anything.

Stick to truth, but we shall succeed, may be slowly, but surely.  

Pray all the time, read all the scriptures in the world, and worship all the gods there are but unless you realize the Truth, there is no freedom.

Practice truthfulness.Tweleve years of absolute truthfulness in thought, word and deed gives a man what he wills.

We are what our thoughts have made us; so take care about what you think. Words are secondary. Thoughts live; they travel far.
All truth is eternal. Truth is nobody’s property; no race, no individual can lay any exclusive claim to it. Truth is the nature of all souls."

Good motives, sincerity, and infinite love can conquer the world. One single soul possessed of these virtues can destroy the dark designs of millions of hypocrites and brutes.

The ignorant man, by prayer and devotion, can reach beyond the philosopher. To know God, no philosophy is necessary. Our duty is not to disturb the faith of others.

First have faith in yourselves.Know that though one may be a little bubble and another may be a mountain high wave, yet behind both the bubble and the wave there is the infinite ocean.

Accept the beneficial and discard the pleasant.

It is good and very grand to conquer external nature, but grander still it is to conquer internal nature.

If a man with an ideal makes a thousand mistakes, I am sure that the man without an ideal makes fifty thousand. Therefore, it is better to have an ideal.

If you have assimilated five ideas, and made them your life and character, you have more education than anyman who has got by heart a whole library.

Do good to all, like everyone, but do not love anyone. 
If you really want the good of others, the whole universe may stand against you and cannot hurt you. It must crumble before your power of the Lord Himself in you if you are sincere and really unselfish.

Out of purity and silence comes the word of power.

In a conflict between the heart and the brain, follow your heart. "

When once you consider an action, do not let anything dissuade you. Consult your heart, not others, and then follow its dictates.

Perfection does not come from belief or faith. Talk does not count for anything. Parrots can do that. Perfection comes through selfless work.
Please everyone without becoming a hypocrite or a coward.
You have to grow from the inside out. None can teach you,
none can make you spiritual. There is no other teacher but your own soul.

The great secret of true success, of true happiness, is this:
the man or woman who asks for no return, the perfectly unselfish person, is the most successful."

Ask nothing; want nothing in return. Give what you have to give; it will come back to you, but do not think of that now."
"Learn everything that is good from others, but bring it in, and in your own way absorb it; do not become others."
A few heart-whole, sincere, and energetic men and women can do more in a year than a mob in a century."

"Do one thing at a Time, and while doing it put your whole Soul into it to the exclusion of all else."

Have Faith in Man, whether he appears to you to be a very learned one or a most ignorant one."

The more we come out and do good to others, the more our hearts will be purified, and God will be in them."

Above all, beware of compromises. Hold on to your own principles in weal or woe and never adjust them to others’.

"It is the Level-headed Man, the Calm Man, of Good Judgement and cool nerves, of Great sympathy and love, who does good work and so does good to himself."

Neither money pays, nor name pays, nor fame, nor learning; it is CHARACTER that cleave through adamantine walls of difference”

We want that education by which character is formed, strength of mind is increased, the intellect is expanded, and by which one can stand on ones feet.

In eating, dressing or lying, in singing or playing, in enjoyment or disease, always manifest the highest moral courage.If you can build your character after such an ideal, then a thousand others will follow.

Help if you can; if you cannot, fold your hands and stand by and see things go on. Do not injure, if you cannot render help”
Three things are necessary to make every man great, every nation great”

1.Conviction of the powers of goodness

2.Absence of jealousy and suspicion

3.Helping all who are trying to be and to do good.

Nature wants us to react, to return blow for blow, cheating for cheating,
lie for lie, to hit back with all our might, then it requires a super divine power not hit back, to keep control, to be unattached”

The very essence of education is concentration of mind, not collecting of facts. Develop the power of concentration of mind and detachment and then with a perfect instrument collect facts at will.

Persons are but the embodiments, the illustration of principles. If the principles are there, the persons will come by the thousands and millions.

A "GOOD WORLD" A "HAPPY WORLD" AND SOCIAL PROGRESS are all terms equally intelligible with "Hot Ice" or "dark light".There is no progress without corresponding digression. 


 
Swami vivekananda's words are not ordinary words of inspiration. Each word of his utterances is potent with a latent power.I tried my best to bring out the gist of his sayings. There are many quotes and I made a small attempt to forward a few of his quotes and utterances. 
 
Every quote and utterances of swami vivekanada has a great power. In many speeches he used to oft quote one of the sayings of his mother :
 
"Remain pure all your life; guard your own honor and never transgress the honor of others. Be very tranquil, but when necessary, harden your heart.  
 
 
A mere reading of the ideas presented here won't do.The ideas must be aasimilated and should be put in to practice.understand the quotes in their spirit and apply to work in the light.Swami

Nobel Prize in Medicine in 1976

Baruch S. Blumberg
D. Carleton Gajdusek

Baruch S. Blumberg

D. Carleton Gajdusek

The Nobel Prize in Physiology or Medicine 1976 was awarded jointly to Baruch S. Blumberg and D. Carleton Gajdusek "for their discoveries concerning new mechanisms for the origin and dissemination of infectious diseases"

Mother Theresa....Indian of Albaninan orgin

Mother Theresa

mother theresaPerhaps of of the most famous mothers in history wasn't technically a mother herself, yet millions who she provided care for would look up to her. Mother Theresa was her name, and she has gone down in history as one of the most influential humanitarians to ever walk the earth, spending her entire adult life taking care of the poor, homeless, and the sick in the name of Jesus Christ.
Born Agnes Gonxha in 1910, Theresa would grow up as a Roman Catholic following the death of her father at a very young age, and this upbringing would have an important effect on her work later in life. At the age of 12 she would become obsessed with the work of missionaries and decide to dedicate her life to their work.
She left her native home in Albania at the age of 18 to begin her missionary life with the Sisters of Loreto, never to see her family again. After a stay in Ireland to learn English, Theresa would then head to India where she cared for the sick and poor for many years.
In September of 1946 Theresa would experience what she described as the "call within the call". This is where Theresa decided to leave the convent in 1948 to devote her life to helping those within the poorest sections of Calcutta. There she would being schooling the children of the slums and begin a small movement of supporters to help he with her work.
In 1950, this work would culminate in "The Missionaries of Charity", dedicated to caring for the poorest of people that Theresa referred to as "the hungry, the naked, the homeless, the crippled, the blind, the lepers, all those people who feel unwanted, unloved, uncared for throughout society, people that have become a burden to the society and are shunned by everyone."
Over the years, these missionaries would go on to assist the poor in countries worldwide, helping not just the poor but also those who have lived through floods, famine and other natural disasters to helping orphanages and AIDS hospices, alcoholics, and others suffering. This organization of charity would become an official International Association in 1969; today it has thousands of nuns organizing millions of co-workers worldwide.
While she has been criticized by many for her obvious affiliations to her Catholic religion, her work at helping those less fortunate in the world cannot be denied. Theresa fought hard to help spread the work she and the Missionaries of Charity accomplished to nations who at first rejected it, and traveled to areas such as Ethiopia and Chernobyl to see her work help others first hand.
Mother Theresa was given an official state funeral by the Indian Government in death in 1997. She had won numerous important Indian awards over the years such as the Padma Shri in 1962. Other awards would continue to follow, including the Jawaharlal Neru Award for International Understanding in 1972, and the highest civilian award known as the Bharat Ratna in 1980. Even though se received this recognition, her reception to the people at the time in India wasn't necessarily mutual.
Critics pointed out that a negative appearance of Calcutta may have been interpreted through her work, and others often reflected on her opposition to the Hindu religion that many throughout India were affiliated with. Politics frequently arose around Theresa's "non-political" agendas related to her opinions on divorce and abortion, as she obviously did not favor these actions due to her faith in Christ and Catholicism. Many at the time often wondered if her actions were playing a larger role in trying to convert others to her beliefs and religion. Still, even some her most outspoken critics praised and favored her in her death.
mother theresaFor her work in southeast asia, Mother Theresa earned the Ramon Magsayay Award for International Understanding in 1962. In 1971, Theresa had the honor of receiving were the Pope John XXIII Peace Prize, presented to her by Pope John Paul for Christian charity work, and the Pacem in Terris Award in 1976. By this time, Theresa was known worldwide for her work, mostly in part to these awards and an earlier documentary entitled Something Beautiful for God, both a film in 1969 and book in 1971. It was in this film that a "divine light" supposedly lit from Mother Theresa during a shoot in less than desirable lighting conditions.
As her celebrity rose, so did her acceptance by some nations and some opposition by others. Critics would create politics around the finances surrounding Theresa in addition to her supposed affiliations with particular governments, including the United States, where she was named an honorary citizen in 1986 by Ronald Regan, and the United Kingdom. Still, she continued to be recognized in various parts of the world for her continued philanthropy, obtaining the Albert Scweitzer International Prize in 1975. She was granted the Balzan prize in 1978 for "promoting humanity, peace, and brotherhood amoung peoples". Finally, in 1979, she was awarded the highly regarded Nobel Peace Prize, donating the financial reward to her poor in Calcutta.
Throughout her life as a believer in Jesus Christ, Mother Theresa has followed a path towards sainthood. After in death in 1997, the Holy See, or central governing body of the Catholic Church, began the steps that needed to be taken for Theresa to receive Beatification. This was a recognition by the church that Theresa had accented into heaven and was to be considered one to have achieved sainthood.
Part of this process involved evidence that Theresa had indeed performed a miracle, and called upon an incident where a patient witnessed a "beam of light" that shun from a picture of Theresa, curing a tumor. Of course, in the proceedings, witnesses denounced the miracle in addition to critics of Theresa questioning Theresa's motivations for work throughout her career.
Nonetheless, in October of 2003, her beatification took place and the title of "Blessed" given to one of the greatest "mothers" to have ever lived.

Tuesday, January 11, 2011

Two scientific Boses who should have but never won Nobels

Einstein’s young collaborator Satyendra Nath Bose (1894-1974) should have been a winner, and has the Boson particle and Bose-Einstein statistics named after him.
Much before him, Sir Jagadish Chandra Bose (1858-1937) deserved to win in two fields: physics and medicine. Marconi and Braun shared the 1909 Physics Prize “for development of wireless telegraphy” – but this was an achievement in which Bose shared more than equally though he was deprived of due honour and recognition, his work coming to light only in the last decade. In Physiology/Medicine, Bose’s work was so far ahead of his time it seemed controversial to lesser men. He introduced new delicate instruments, one of which, the crescograph magnified small movements in plant growth 10 million times. Among his numerous other contributions were demonstration of a parallelism between plant and animal tissues. I should declare an interest as JC Bose was a friend of my great grandfather’s, and his visits to our home are still remembered by my father, now in his 90s. I said in 2007 about him “had Bose been less of a great scientific soul and even slightly more of a businessman than he was by temperament and character, he should have been a winner too”.

Srinivasa Ramanujan..the forgotten Mathematician from India


Srinivasa Ramanujan
 
Ramanujan’s life is full of strange contrasts. He had no formal training in mathematics but yet “he was a natural mathematical genius, in the class of Gauss and Euler.” Probably Ramanujan’s life has no parallel in the history of human thought. Godfrey Harold Hardy, (1877-1947), who made it possible for Ramanujan to go to Cambridge and give formal shape to his works, said in one of his lectures given at Harvard Universty (which later came out as a book entitled Ramanujan: Twelve Lectures on Subjects Suggested by His Life and Work): “I have to form myself, as I have never really formed before, and try to help you to form, some of the reasoned estimate of the most romantic figure in the recent history of mathematics, a man whose career seems full of paradoxes and contradictions, who defies all cannons by which we are accustomed to judge one another and about whom all of us will probably agree in one judgement only, that he was in some sense a very great mathematician.”
Srinivasa Ramanujan Iyengar (best known as Srinivasa Ramanujan) was born on December 22, 1887, in Erode about 400 km from Chennai, formerly known as Madras where his mother’s parents lived. After one year he was brought to his father’s town, Kumbakonam. His parents were K. Srinivasa Iyengar and Komalatammal. He passed his primary examination in 1897, scoring first in the district and then he joined the Town High School. In 1904 he entered Kumbakonam’s Government College as F.A. student. He was awarded a scholarship. However, after school, Ramanujan’s total concentration was focussed on mathematics. The result was that his formal education did not continue for long. He first failed in Kumbakonam’s Government College. He tried once again in Madras from Pachaiyappa’s College but he failed again.
While at school he came across a book entitled A Synopsis of Elementary Results in Pure and Applied Mathematics by George Shoobridge Carr. The title of the book does not reflect its contents. It was a compilation of about 5000 equations in algebra, calculus, trigonometry and analytical geometry with abridged demonstrations of the propositions. Carr had compressed a huge mass of mathematics that was known in the late nineteenth century within two volumes. Ramanujan had the first one. It was certainly not a classic. But it had its positive features. According to Kanigel, “one strength of Carr’s book was a movement, a flow to the formulas seemingly laid down one after another in artless profusion that gave the book a sly seductive logic of its own.” Thisbook had a great influence on Ramanujan’s career. However, the book itself was not very great. Thus Hardy wrote about the book: “He (Carr) is now completely forgotten, even in his college, except in so far as Ramanujan kept his name alive”. He further continued, “The book is not in any sense a great one, but Ramanujan made it famous and there is no doubt it influenced him (Ramanujan) profoundly”. We do not know how exactly Carr’s book influenced Ramanujan but it certainly gave him a direction. `It had ignited a burst of fiercely single-minded intellectual activity’. Carr did not provide elaborate demonstration or step by step proofs. He simply gave some hints to proceed in the right way. Ramanujan took it upon himself to solve all the problems in Carr’s Synopsis. And as E. H. Neville, an English mathematician, wrote : “In proving one formula, as he worked through Carr’s synopsis, he discovered many others, and he began the practice of compiling a notebook.” Between 1903 and 1914 he had three notebooks.
While Ramanujan made up his mind to pursue mathematics forgetting everything else but then he had to work under extreme hardship. He could not even buy enough paper to record the proofs of his results. Once he said to one of his friends, “when food is problem, how can I find money for paper? I may require four reams of paper every month.” In fact Ramanujan was in a very precarious situation. He had lost his scholarship. He had failed in examination. What is more, he failed to prove a good tutor in the subject which he loved most.
At this juncture, Ramanujan was helped by R. Ramachandra Rao, then Collector of Nellore. Ramchandra Rao was educated at Madras Presidency College and had joined the Provincial Civil Service in 1890. He also served as Secretary of the Indian Mathematical Society and even contributed solution to problem posed in its Journal. The Indian Mathematical Society was founded by V. Ramaswami Iyer, a middle-level Government servant, in 1906. Its Journal put Ramanujan on the world’s mathematical map. Ramaswami Iyer met Ramanujan sometime late in 1910. Ramaswami Iyer gave Ramanujan notes of introduction to his mathematical friends in Chennai (then Madras). One of them was P.V. Seshu Iyer, who earlier taught Ramanujan at the Government College. For a short period (14 months) Ramanujan worked as clerk in the Madras Port Trust which he joined on March 1, 1912. This job he got with the help of S. Narayana Iyer.
Ramanujan’s name will always be linked to Godfrey Harold Hardy, a British mathematician. It is not because Ramanujan worked with Hardy at Cambridge but it was Hardy who made it possible for Ramanujan to go to Cambridge. Hardy, widely recognised as the leading mathematician of his time, championed pure mathematics and had no interest in applied aspects. He discovered one of the fundamental results in population genetics which explains the properties of dominant, and recessive genes in large mixed population, but he regarded the work as unimportant.
Encouraged by his well-wishers, Ramanujan, then 25 years old and had no formal education, wrote a letter to Hardy on January 16, 1913. The letter ran into eleven pages and it was filled with theorems in divergent series. Ramanujan did not send proofs for his theorems. He requested Hardy for his advice and to help getting his results published. Ramanujan wrote : “I beg to introduce myself to you as a clerk in the Accounts Department of the Port Trust Office at Madras on a salary of only £ 20 per annum. I have had no university education but I have undergone the ordinary school course. After leaving school I have been employing the spare time at my disposal to work at mathematics. I have not trodden through the conventional regular course which is followed in a university course, but I am striking out a new path for myself. I have made a special investigation of divergent series in general and the results I get are termed by the local mathematicians as “startling“… I would request you to go through the enclosed papers. Being poor, if you are convinced that there is anything of value I would like to have my theorems published. I have not given the actual investigations nor the expressions that I get but I have indicated the lines on which I proceed. Being inexperienced I would very highly value any advice you give me “. The letter has become an important historical document. In fact, ‘this letter is one of the most important and exciting mathematical letters ever written’. At the first glance Hardy was not impressed with the contents of the letter. So Hardy left it aside and got himself engaged in his daily routine work. But then he could not forget about it. In the evening Hardy again started examining the theorems sent by Ramanujan. He also requested his colleague and a distinguished mathematician, John Edensor Littlewood (1885-1977) to come and examine the theorems. After examining closely they realized the importance of Ramanujan’s work. As C.P. Snow recounted, ‘before mid-night they knew and knew for certain’ that the writer of the manuscripts was a man of genius’. Everyone in Cambridge concerned with mathematics came to know about the letter. Many of them thought `at least another Jacobi in making had been found out’. Bertrand Arthur William Russell (1872-1970) wrote to Lady Ottoline Morell. “I found Hardy and Littlewood in a state of wild excitement because they believe, they have discovered a second Newton, a Hindu Clerk in Madras … He wrote to Hardy telling of some results he has got, which Hardy thinks quite wonderful.”
Fortunately for Ramanujan, Hardy realised that the letter was the work of a genius. In the next three months Ramanujan received another three letters from Hardy. However, in the beginning Hardy responded cautiously. He wrote on 8 February 1913. To quote from the letter. “I was exceedingly interested by your letter and by the theorems which you state. You will however understand that, before I can judge properly of the value of what you have done it is essential that I should see proofs of some of your assertions … I hope very much that you will send me as quickly as possible at any rate a few of your proofs, and follow this more at your leisure by more detailed account of your work on primer and divergent series. It seems to me quite likely that you have done a good deal of work worth publication; and if you can produce satisfactory demonstration I should be very glad to do what I can to secure it” .
In the meantime Hardy started taking steps for bringing Ramanujan to England. He contacted the Indian Office in London to this effect. Ramanujan was awarded the first research scholarship by the Madras University. This was possible by the recommendation of Gilbert Walker, then Head of the Indian Meteorological Department in Simla. Gilbert was not a pure mathematician but he was a former Fellow and mathematical lecturer at Trinity College, Cambridge. Walker, who was prevailed upon by Francis Spring to look through Ramanujan’s notebooks wrote to the Registrar of the Madras University : “The character of the work that I saw impressed me as comparable in originality with that of a Mathematical Fellow in a Cambridge College; it appears to lack, however, as might be expected in the circumstances, the completeness and precision necessary before the universal validity of the results could be accepted. I have not specialised in the branches of pure mathematics at which he worked, and could not therefore form a reliable estimate of his abilities, which might be of an order to bring him a European reputation. But it was perfectly clear to me that the University would be justified in enabling S. Ramanujan for a few years at least to spend the whole of his time on mathematics without any anxiety as to his livelihood.”
Ramanujan was not very eager to travel abroad. In fact he was quite apprehensive. However, many of his well-wishers prevailed upon him and finally Ramanujan left Madras by S.S. Navesa on March 17, 1914. Ramanujan reached Cambridge on April 18, 1914. When Ramanujan reached England he was fully abreast of the recent developments in his field. This was described by J. R. Newman in 1968: “Ramanujan arrived in England abreast and often ahead of contemporary mathematical knowledge. Thus, in a lone mighty sweep, he had succeeded in recreating in his field, through his own unaided powers, a rich half century of European mathematics. One may doubt whether so prodigious a feat had ever been accomplished in the history of thought.”
Today it is simply futile to speculate about what would have happened if Ramanujan had not come in contact with Hardy. It could happen either way. But then Hardy should be given due credit for recognizing Ramanujan’s originality and helping him to carry out his work. Hardy himself was very clear about his role. “Ramanujan was”, Hardy wrote, “my discovery. I did not invent him — like other great men, he invented himself — but I was the first really competent person who had the chance to see some of his work, and I can still remember with satisfaction that I could recognize at once what I treasure I had found.”
It may be noted that before writing to Hardy, Ramanujan had written to two well-known Cambridge mathematicians viz., H.F. Baker and E.W. Hobson. But both of them had expressed their inability to help Ramanujan.
Ramanujan was awarded the B.A. degree in March 1916 for his work on ‘Highly composite Numbers’ which was published as a paper in the Journal of the London Mathematical Society. He was the second Indian to become a Fellow of the Royal Society in 1918 and he became one of the youngest Fellows in the entire history of the Royal Society. He was elected “for his investigation in Elliptic Functions and the Theory of Numbers.” On 13 October 1918 he was the first Indian to be elected a Fellow of Trinity College, Cambridge.
Much of Ramanujan’s mathematics comes under the heading of number theory — a purest realm of mathematics. The number theory is the abstract study of the structure of number systems and properties of positive integers. It includes various theorems about prime numbers (a prime number is an integer greater than one that has not integral factor). Number theory includes analytic number theory, originated by Leonhard Euler (1707-89); geometric theory - which uses such geometrical methods of analysis as Cartesian co-ordinates, vectors and matrices; and probabilistic number theory based on probability theory. What Ramanujan did will be fully understood by a very few. In this connection it is worthwhile to note what Hardy had to say of the work of pure mathematicians: “What we do may be small, but it has certain character of permanence and to have produced anything of the slightest permanent interest, whether it be a copy of verses or a geometrical theorem, is to have done something beyond the powers of the vast majority of men.” In spite of abstract nature of his work Ramanujan is widely known.
Ramanujan was a mathematical genius in his own right on the basis of his work alone. He worked hard like any other great mathematician. He had no special, unexplained power. As Hardy, wrote: “I have often been asked whether Ramanujan had any special secret; whether his methods differed in kind from those of other mathematicians; whether there was anything really abnormal in his mode of thought. I cannot answer these questions with any confidence or conviction; but I do not believe it. My belief that all mathematicians think, at bottom, in the same kind of way, and that Ramanujan was no exception.”
Of course, as Hardy observed Ramanujan “combined a power of generalization, a feeling for form and a capacity for rapid modification of his hypotheses, that were often really startling, and made him, in his peculiar field, without a rival in his day.
Here we do not attempt to describe what Ramanujan achieved. But let us note what Hardy had to say about the importance of Ramanujan’s work. “Opinions may differ as to the importance of Ramanujan’s work, the kind of standard by which it should be judged and the influence which it is likely to have on the mathematics of the future. It has not the simplicity and the inevitableness of the greatest work; it would be greater if it were less strange. One gift it shows which no one will deny—profound and invincible originality.”
The Norwegian mathematician Atle Selberg, one of the great number theorists of this century wrote : “Ramanujan’s recognition of the multiplicative properties of the coefficients of modular forms that we now refer to as cusp forms and his conjectures formulated in this connection and their later generalization, have come to play a more central role in the mathematics of today, serving as a kind of focus for the attention of quite a large group of the best mathematicians of our time. Other discoveries like the mock-theta functions are only in the very early stages of being understood and no one can yet assess their real importance. So the final verdict is certainly not in, and it may not be in for a long time, but the estimates of Ramanujan’s nature in mathematics certainly have been growing over the years. There is doubt no about that.”
Often people tend to speculate what Ramanujan would have achieved if he had not died or if his exceptional qualities were recognised at the very beginning. There are many instances of such untimely death of gifted persons, or rejection of gifted persons by the society or the rigid educational system. In mathematics we may cite the cases of Niels Henrik Abel (1809-29) and Evarista Galois (1811-32). Abel solved one of the great mathematical problems of his day - finding a general solution for a class equations called quintiles. Abel solved the problem by proving that such a solution was impossible. Galois pioneered the branch of modern mathematics known as group theory. What is important is that we should recognise the greatness of such people and take inspiration from their work.
Even after more than 80 years of the death of Ramanujan the situation is not very different as far the rigidity of the education system. Today also a ‘Ramanujan’ is not likely to get a chance to pursue his career. This situation remains very much similar as described by JBS Haldane (1982-1964), a British born geneticist and philosopher who spent last part of his life in India. Haldane said : “Today in India Ramanujan could not get even a lectureship in a rural college because he had no degree. Much less could he get a post through the Union Public Service Commission. This fact is a disgrace to India. I am aware that he was offered a chair in India after becoming a Fellow of the Royal Society. But it is scandalous that India’s great men should have to wait for foreign recognition. If Ramanujan’s work had been recognised in India as early it was in England, he might never have emigrated and might be alive today. We can cast the blame for Ramanujan’s non-recognition on the British Raj. We cannot do so when similar cases occur today...”
Nehru’s statement given at the beginning is very much valid even today. And for these very reasons the story of Ramanujan should be told and retold to our younger people particularly to those who aspire to do something extraordinary but feel dejected under the prevailing circumstances. And in this connection it is worthwhile to remember what Chandrasekhar had to say: “I can recall the gladness I felt at the assurance that one brought up under circumstances similar to my own could have achieved what I could not grasp. The fact that Ramanujan’s early years were spent in a scientifically sterile atmosphere, that his life in India was not without hardships that under circumstances that appeared to most Indians as nothing short of miraculous, he had gone to Cambridge, supported by eminent mathematicians, and had returned to India with very assurance that he would be considered, in time as one of the most original mathematicians of the century — these facts were enough, more than enough, for aspiring young Indian students to break their bands of intellectual confinement and perhaps soar the way what Ramanujan had.
” As someone has written “Ramanujan did mathematics for its own sake, for thrill that he got in seeing and discovering unusual relationships between various mathematical objects.” Today Ramanujan’s work has some applications in particle physics or in the calculation of pi up to a very large number of decimal places. His work on Rieman’s Zeta Function has been applied to the pyrometry, the investigations of the temperature of furnaces. His work on the Partition Numbers resulted in two applications — new fuels and fabrics like nylons. But then highlighting the importance of the application side Ramanujan’s work is really not very important.
Ramanujan died of tuberculosis in Kumbakonam on April 26, 1920. He was only 32 years old. “It was always maths ... Four days before he died he was scribbling,” said Janaki, his wife. The untimely death of Ramanujan was most unfortunate particularly so when we take into account the circumstances under which he died. As Times Magazine rightly wrote: “There is something peculiarly sad in the spectacle of genius dying young, dying with the first sweets of recognition and success tasted, but before the full recognition of powers that lie within.
” The only Ramanujan Museum in the country, founded by Shri P. K. Srinivasan, a mathematics teacher, operates from March 1993 in the Avvai Academy, Royapuram, Madras. The achievement of Ramanujan was so great that those who can really grasp the work of Ramanujan ‘may doubt that so prodigious a feat had ever been accomplished in the history of thought’.
Roger Guillemin
Andrew V. Schally
Rosalyn Yalow

Roger Guillemin

Andrew V. Schally

Rosalyn Yalow

The Nobel Prize in Physiology or Medicine 1977 was divided, one half jointly to Roger Guillemin and Andrew V. Schally "for their discoveries concerning the peptide hormone production of the brain" and the other half to Rosalyn Yalow "for the development of radioimmunoassays of peptide hormones".

Leonardo da Vinci..a brief history on the legend

The Life and Times of Leonardo Da Vinci 

A little history on the legend

At age 14 (although I've also read 17), Leonardo and his father moved to Florence, where he apprenticed to Andrea di Cione, known as Verrocchio. Among the painters apprenticed or associated with the workshop and also to become famous, were Ghirlandaio, Perugino, Botticelli, and Lorenzo di Credi.

According to tradition, Leonardo posed for Verrocchio's David, as seen at left.

In the studios of men like Verrocchio's, artists were regarded primarily as craftsmen and only the master such as Verrocchio had social standing in the community. It was when the student created their "masterwork" that they could themselves be considered a master.

Leonardo would have been exposed to a vast range of technical skills and had the opportunity to learn drafting, chemistry, metallurgy, leather working, carpentry, and mechanics. The study obviously included artistic skills of drawing, painting, sculpting and modeling.

Leonardo Da Vinci was a quick study and his genius soon eclipsed that of his master and by age 20 he joined the painter's guild of Florence. From there he began getting commissions to work on projects from various people of high standing and wealth throughout current day Italy.

Da Vinci Trivia

A little known bit of trivia about Leonardo Da Vinci was that he may have been dyslexic. He would often write his notes backwards, which is common with left-handed, dyslexic people.
Mona Lisa

Da Vinci: The Artist 

Although being most known for his paintings, he was not a prolific painter, instead he was more of a draftsmen, keeping journals filled with sketches and detailed drawings. One of the things that he is known for is his study of human emotions, often following a subject around for hours trying to get a feel for their expressions.

He was also known for his scientific approach to light and shadows, allowing his paintings to take on a three dimensional feel. Da Vinci paintings were realistic, which was not the norm for that era. His influence on painting realism became the standard for painters who followed in the 16th century.

The Last Supper 



The Last Supper represents the scene from the final days of Jesus, as narrated in the Gospel of John 13:21, when Jesus announced that one of his Twelve apostles would betray him.
The Last Supper is one of his best-known and worst-preserved pieces of art from Da Vinci. Doomed from the start by Leonardo's experimental technique, the mural began to deteriorate even before the artist's death. Within 50 years it was almost indecipherable, and it was repainted twice during the 18th century.

The painting continued to suffer, as Napoleon's soldiers almost destroyed it. If not bad enough, later the monks that cared for it actually cut a door through the bottom of the painting!

Much later, the painting miraculously survived the allied bombings of World War II. Finally, now it is well cared-for in Santa Maria delle Grazie, in Milan Italy.
Some of his flying machines

Da Vinci: The Inventor 

He was well regarded and valued as an engineer during his time. In 1502, Leonardo produced a drawing of a single span 720-foot (240 m) bridge as part of a civil engineering project for Ottoman Sultan Beyazid II of Istanbul. The bridge was intended to span an inlet at the mouth of the Bosporus known as the Golden Horn. Beyazid did not pursue the project, because he believed that such a construction was impossible.


Leonardo's vision was resurrected in 2001 when a smaller bridge based on his design was constructed in Norway.

Golden Horn" bridge built on October 31, 2001 in Oslo, Norway

A Short List of his Inventions 

He had many firsts

He was clearly a man ahead of his time. Here is a list of just a few of his inventions and ideas. He was truly an amazing man!
  • He sketched the first parachute
  • The first helicopter
  • The first airplane
  • The first tank
  • The first repeating rifle
  • A swinging bridge
  • A paddle boat
  • The first 'motor' car
  • A machine for testing the tensile strength of wire
  • A calculator
  • A double hull for ships and boats

The Genius of Da Vinci 

Genius Of Leonardo Da Vinci


Virtuvius

Da Vinci: The Scientist 

Da Vinci was known as an exceptional scientist. He practiced more as an observer and theorist.
Da Vinci documented scientific theories, such as a rudimentary theory of plate tectonics. During the 1490s he studied mathematics under Luca Pacioli and sketched various complex shapes, in a skeletal layout to be engraved as plates for Pacioli's book Divina Proportione, published in 1509. In the book, Da Vinci is credited with first ever published drawing of a Rhombicuboctahedron (at left) was done by Da Vinci, in the Divina Proportione.


In addition, he quickly became master of topographic anatomy, drawing many studies of muscles, tendons and other visible anatomical features, as seen to the right. Leonardo's formal training in the anatomy of the human body began with his apprenticeship to Verrocchio. His teacher insisted that all his students learn anatomy. Leonardo closely observed and recorded the effects of age and of human emotion on the physiology, in particular; rage.

His practice was to describe it in utmost detail. Since he had no formal training in science, his scientific genius was less highly regarded by his contemporaries than it would have been otherwise.

Even though he studied his subjects by careful observations, he did take part in dissecting human and animal corpses, after being given permission by various hospitals.

A page from Leonardo's journal showing his study of a foetus in the womb (c. 1510), as seen at left.


Pink

Da Vinci was often known to wear pink to make his complexion look more "fresh"